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The Effect of Trim5 Polymorphisms on the Clinical Course of HIV-1 Infection

The antiviral factor tripartite interaction motif 5α (Trim5α) restricts a broad range of retroviruses in a species-specific manner. Although human Trim5α is unable to block HIV-1 infection in human cells, a modest inhibition of HIV-1 replication has been reported. Recently two polymorphisms in the T...

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Detalles Bibliográficos
Autores principales:	van Manen, Daniëlle, Rits, Maarten A. N, Beugeling, Corrine, van Dort, Karel, Schuitemaker, Hanneke, Kootstra, Neeltje A
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2008
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2222955/ https://www.ncbi.nlm.nih.gov/pubmed/18248091 http://dx.doi.org/10.1371/journal.ppat.0040018

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