Antisense Knock Out of the Inositol 1,3,4,5-Tetrakisphosphate Receptor GAP1(IP4BP) in the Human Erythroleukemia Cell Line Leads to the Appearance of Intermediate Conductance K(Ca) Channels that Hyperpolarize the Membrane and Enhance Calcium Influx

To study the role of the inositol 1,3,4,5-trisphosphate–binding protein GAP1(IP4BP) in store-operated Ca(2+) entry, we established a human erythroleukemia (HEL) cell line in which the expression of GAP1(IP4BP) was substantially reduced by transfection with a vector containing antisense DNA under con...

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Detalles Bibliográficos
Autores principales: Lu, Xinghua, Fein, Alan, Feinstein, Maurice B., O'Rourke, Flavia A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1999
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2222987/
https://www.ncbi.nlm.nih.gov/pubmed/9874690

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