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Randomized comparison of etoposide pharmacokinetics after oral etoposide phosphate and oral etoposide.
Etoposide phosphate is a water-soluble prodrug of etoposide. The plasma pharmacokinetics of etoposide following oral administration of etoposide phosphate or oral etoposide were compared. Seventeen patients with solid tumours were enrolled to receive oral etoposide phosphate 125 mg m(-2) on days 1-5...
Autores principales: | de Jong, R. S., Mulder, N. H., Uges, D. R., Kaul, S., Winograd, B., Sleijfer DTh, Groen, H. J., Willemse, P. H., van der Graaf, W. T., de Vries, E. G. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
1997
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2223531/ https://www.ncbi.nlm.nih.gov/pubmed/9184183 |
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