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EFFECTS OF CORTISONE ON RAT LIVER MITOCHONDRIA
Experiments were designed to determine the effects of parenteral administration of cortisone on mitochondrial numbers of rat liver cells. Observations were made in three ways: (1) after osmic acid fixation and appropriate stain, (2) by phase microscopy on intact cells, (3) by actual enumeration of m...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
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The Rockefeller University Press
1955
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2223815/ https://www.ncbi.nlm.nih.gov/pubmed/13242589 |
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author | Lowe, Charles Upton MacKinney, Deloris Sarkaria, Daljit |
author_facet | Lowe, Charles Upton MacKinney, Deloris Sarkaria, Daljit |
author_sort | Lowe, Charles Upton |
collection | PubMed |
description | Experiments were designed to determine the effects of parenteral administration of cortisone on mitochondrial numbers of rat liver cells. Observations were made in three ways: (1) after osmic acid fixation and appropriate stain, (2) by phase microscopy on intact cells, (3) by actual enumeration of mitochondria and nuclei to provide data on mitochondria per cell. The results of the experiments indicate that the mitochondria per cell are significantly reduced under the conditions used. Each experimental approach provided similar data, and each tended to support the results obtained from the others. |
format | Text |
id | pubmed-2223815 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1955 |
publisher | The Rockefeller University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-22238152008-05-01 EFFECTS OF CORTISONE ON RAT LIVER MITOCHONDRIA Lowe, Charles Upton MacKinney, Deloris Sarkaria, Daljit J Biophys Biochem Cytol Article Experiments were designed to determine the effects of parenteral administration of cortisone on mitochondrial numbers of rat liver cells. Observations were made in three ways: (1) after osmic acid fixation and appropriate stain, (2) by phase microscopy on intact cells, (3) by actual enumeration of mitochondria and nuclei to provide data on mitochondria per cell. The results of the experiments indicate that the mitochondria per cell are significantly reduced under the conditions used. Each experimental approach provided similar data, and each tended to support the results obtained from the others. The Rockefeller University Press 1955-05-25 /pmc/articles/PMC2223815/ /pubmed/13242589 Text en Copyright © Copyright, 1955, by The Rockefeller Institute for Medical Research |
spellingShingle | Article Lowe, Charles Upton MacKinney, Deloris Sarkaria, Daljit EFFECTS OF CORTISONE ON RAT LIVER MITOCHONDRIA |
title | EFFECTS OF CORTISONE ON RAT LIVER MITOCHONDRIA |
title_full | EFFECTS OF CORTISONE ON RAT LIVER MITOCHONDRIA |
title_fullStr | EFFECTS OF CORTISONE ON RAT LIVER MITOCHONDRIA |
title_full_unstemmed | EFFECTS OF CORTISONE ON RAT LIVER MITOCHONDRIA |
title_short | EFFECTS OF CORTISONE ON RAT LIVER MITOCHONDRIA |
title_sort | effects of cortisone on rat liver mitochondria |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2223815/ https://www.ncbi.nlm.nih.gov/pubmed/13242589 |
work_keys_str_mv | AT lowecharlesupton effectsofcortisoneonratlivermitochondria AT mackinneydeloris effectsofcortisoneonratlivermitochondria AT sarkariadaljit effectsofcortisoneonratlivermitochondria |