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Phase II trial of raltitrexed ('Tomudex') in advanced small-cell lung cancer.
Raltitrexed, a thymidylate synthase inhibitor, was given to 21 patients with advanced small-cell lung cancer, at a dose of 3 mg m(-2) as a 15-min intravenous infusion at 21-day intervals. All of the patients had extensive disease and 17 had received prior therapy. Patients with disease refractory to...
Autores principales: | Woll, P. J., Basser, R., Le Chevalier, T., Drings, P., Perez Manga, G., Adenis, A., Seymour, L., Smith, F., Thatcher, N. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
1997
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2223947/ https://www.ncbi.nlm.nih.gov/pubmed/9231930 |
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