THE DISTRIBUTION OF NEWLY SYNTHESIZED DNA IN MITOTIC DIVISION

The chromosomes of Crepis capillaris were labelled with thymidine-2-C(14) in their DNA fraction. Quantitative analysis of the distribution of newly synthesized DNA in postmetaphase stages of the division following the period of label incorporation led to the conclusion that the new DNA is not necess...

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Detalles Bibliográficos
Autores principales: Plaut, Walter, Mazia, Daniel
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1956
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2223985/
https://www.ncbi.nlm.nih.gov/pubmed/13376635
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author Plaut, Walter
Mazia, Daniel
author_facet Plaut, Walter
Mazia, Daniel
author_sort Plaut, Walter
collection PubMed
description The chromosomes of Crepis capillaris were labelled with thymidine-2-C(14) in their DNA fraction. Quantitative analysis of the distribution of newly synthesized DNA in postmetaphase stages of the division following the period of label incorporation led to the conclusion that the new DNA is not necessarily equally distributed by the mitotic process and that, therefore, chromosome duplication does not involve the equal partition of parental DNA. The implications of these findings with respect to DNA duplication are discussed. An attempt is made to translate the pattern of new DNA distribution into a probable number of units of synthesis per chromosome.
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spelling pubmed-22239852008-05-01 THE DISTRIBUTION OF NEWLY SYNTHESIZED DNA IN MITOTIC DIVISION Plaut, Walter Mazia, Daniel J Biophys Biochem Cytol Article The chromosomes of Crepis capillaris were labelled with thymidine-2-C(14) in their DNA fraction. Quantitative analysis of the distribution of newly synthesized DNA in postmetaphase stages of the division following the period of label incorporation led to the conclusion that the new DNA is not necessarily equally distributed by the mitotic process and that, therefore, chromosome duplication does not involve the equal partition of parental DNA. The implications of these findings with respect to DNA duplication are discussed. An attempt is made to translate the pattern of new DNA distribution into a probable number of units of synthesis per chromosome. The Rockefeller University Press 1956-09-25 /pmc/articles/PMC2223985/ /pubmed/13376635 Text en Copyright © Copyright, 1956, by The Rockefeller Institute for Medical Research
spellingShingle Article
Plaut, Walter
Mazia, Daniel
THE DISTRIBUTION OF NEWLY SYNTHESIZED DNA IN MITOTIC DIVISION
title THE DISTRIBUTION OF NEWLY SYNTHESIZED DNA IN MITOTIC DIVISION
title_full THE DISTRIBUTION OF NEWLY SYNTHESIZED DNA IN MITOTIC DIVISION
title_fullStr THE DISTRIBUTION OF NEWLY SYNTHESIZED DNA IN MITOTIC DIVISION
title_full_unstemmed THE DISTRIBUTION OF NEWLY SYNTHESIZED DNA IN MITOTIC DIVISION
title_short THE DISTRIBUTION OF NEWLY SYNTHESIZED DNA IN MITOTIC DIVISION
title_sort distribution of newly synthesized dna in mitotic division
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2223985/
https://www.ncbi.nlm.nih.gov/pubmed/13376635
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