Polyamine deprivation prevents the development of tumour-induced immune suppression.

Mice grafted with the 3LL (Lewis lung) carcinoma exhibit immune suppression: spleen cells showed decreased spontaneous interleukin 2 (IL-2) production and T-CD4+ and T-CD8+ lymphocyte populations; in addition the polyamine content in the spleen was increased. By treating the mice with a polyamine-de...

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Detalles Bibliográficos
Autores principales: Chamaillard, L., Catros-Quemener, V., Delcros, J. G., Bansard, J. Y., Havouis, R., Desury, D., Commeurec, A., Genetet, N., Moulinoux, J. P.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1997
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2224072/
https://www.ncbi.nlm.nih.gov/pubmed/9252204

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