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AN ELECTRON MICROSCOPE STUDY OF THE EMBRYOLOGY OF THE INTERCALATED DISC IN THE HEART OF THE RABBIT
Prenatal and postnatal cardiac muscle from rabbits has been studied by electron microscopy, after osmium fixation and methacrylate embedding. The observations showed that 1. Cell membranes divide the muscle into cellular units from the youngest embryo which was studied (9½ days after coitus) until t...
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Formato: | Texto |
Lenguaje: | English |
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The Rockefeller University Press
1957
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2224074/ https://www.ncbi.nlm.nih.gov/pubmed/13438902 |
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author | Muir, Alan R. |
author_facet | Muir, Alan R. |
author_sort | Muir, Alan R. |
collection | PubMed |
description | Prenatal and postnatal cardiac muscle from rabbits has been studied by electron microscopy, after osmium fixation and methacrylate embedding. The observations showed that 1. Cell membranes divide the muscle into cellular units from the youngest embryo which was studied (9½ days after coitus) until the adult state. 2. The embryonic muscle cells contain only one nucleus, whereas the adult cell may be multinucleated. 3. At all stages of development, wherever a myofibrillar axis crosses a cellular boundary, the myofilaments are interrupted by an intercalated disc. 4. With age, increase in size and complexity of the discs render them recognisable by the light microscope. |
format | Text |
id | pubmed-2224074 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1957 |
publisher | The Rockefeller University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-22240742008-05-01 AN ELECTRON MICROSCOPE STUDY OF THE EMBRYOLOGY OF THE INTERCALATED DISC IN THE HEART OF THE RABBIT Muir, Alan R. J Biophys Biochem Cytol Article Prenatal and postnatal cardiac muscle from rabbits has been studied by electron microscopy, after osmium fixation and methacrylate embedding. The observations showed that 1. Cell membranes divide the muscle into cellular units from the youngest embryo which was studied (9½ days after coitus) until the adult state. 2. The embryonic muscle cells contain only one nucleus, whereas the adult cell may be multinucleated. 3. At all stages of development, wherever a myofibrillar axis crosses a cellular boundary, the myofilaments are interrupted by an intercalated disc. 4. With age, increase in size and complexity of the discs render them recognisable by the light microscope. The Rockefeller University Press 1957-03-25 /pmc/articles/PMC2224074/ /pubmed/13438902 Text en Copyright © Copyright, 1957, by The Rockefeller Institute for Medical Research |
spellingShingle | Article Muir, Alan R. AN ELECTRON MICROSCOPE STUDY OF THE EMBRYOLOGY OF THE INTERCALATED DISC IN THE HEART OF THE RABBIT |
title | AN ELECTRON MICROSCOPE STUDY OF THE EMBRYOLOGY OF THE INTERCALATED DISC IN THE HEART OF THE RABBIT |
title_full | AN ELECTRON MICROSCOPE STUDY OF THE EMBRYOLOGY OF THE INTERCALATED DISC IN THE HEART OF THE RABBIT |
title_fullStr | AN ELECTRON MICROSCOPE STUDY OF THE EMBRYOLOGY OF THE INTERCALATED DISC IN THE HEART OF THE RABBIT |
title_full_unstemmed | AN ELECTRON MICROSCOPE STUDY OF THE EMBRYOLOGY OF THE INTERCALATED DISC IN THE HEART OF THE RABBIT |
title_short | AN ELECTRON MICROSCOPE STUDY OF THE EMBRYOLOGY OF THE INTERCALATED DISC IN THE HEART OF THE RABBIT |
title_sort | electron microscope study of the embryology of the intercalated disc in the heart of the rabbit |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2224074/ https://www.ncbi.nlm.nih.gov/pubmed/13438902 |
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