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THE CELL IN STARVATION: PHYSIOLOGICAL AND CHEMICAL OBSERVATIONS
Observations made on Amoeba proteus during total inanition revealed the following changes: Dry weight declined progressively, but at a decreasing rate to about 45 per cent of the initial levels when determined in surviving members of a dying population. Protein fell to about 70 per cent of the initi...
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Formato: | Texto |
Lenguaje: | English |
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The Rockefeller University Press
1957
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2224133/ https://www.ncbi.nlm.nih.gov/pubmed/13481026 |
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author | Cohen, Adolph I. |
author_facet | Cohen, Adolph I. |
author_sort | Cohen, Adolph I. |
collection | PubMed |
description | Observations made on Amoeba proteus during total inanition revealed the following changes: Dry weight declined progressively, but at a decreasing rate to about 45 per cent of the initial levels when determined in surviving members of a dying population. Protein fell to about 70 per cent of the initial level. A hexane-alcohol extractable component fell during early starvation then rose to about its initial absolute level in the dying cells. While initially most of this component is probably lipide, it is not certain that other materials are not extracted during cell degeneration. Survival as a function of cell size was studied. No advantage in survival was apparent for any size class. Nucleate cell "halves" likewise showed no survival time differential, unlike a highly significant decrease in the survival of enucleate portions. The maintenance of the initial variance about the mean population weight (after hexane-alcohol extraction) during starvation, likewise supports the idea that survival depends largely on concentration parameters. |
format | Text |
id | pubmed-2224133 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1957 |
publisher | The Rockefeller University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-22241332008-05-01 THE CELL IN STARVATION: PHYSIOLOGICAL AND CHEMICAL OBSERVATIONS Cohen, Adolph I. J Biophys Biochem Cytol Article Observations made on Amoeba proteus during total inanition revealed the following changes: Dry weight declined progressively, but at a decreasing rate to about 45 per cent of the initial levels when determined in surviving members of a dying population. Protein fell to about 70 per cent of the initial level. A hexane-alcohol extractable component fell during early starvation then rose to about its initial absolute level in the dying cells. While initially most of this component is probably lipide, it is not certain that other materials are not extracted during cell degeneration. Survival as a function of cell size was studied. No advantage in survival was apparent for any size class. Nucleate cell "halves" likewise showed no survival time differential, unlike a highly significant decrease in the survival of enucleate portions. The maintenance of the initial variance about the mean population weight (after hexane-alcohol extraction) during starvation, likewise supports the idea that survival depends largely on concentration parameters. The Rockefeller University Press 1957-11-25 /pmc/articles/PMC2224133/ /pubmed/13481026 Text en Copyright © Copyright, 1957, by The Rockefeller Institute for Medical Research |
spellingShingle | Article Cohen, Adolph I. THE CELL IN STARVATION: PHYSIOLOGICAL AND CHEMICAL OBSERVATIONS |
title | THE CELL IN STARVATION: PHYSIOLOGICAL AND CHEMICAL OBSERVATIONS |
title_full | THE CELL IN STARVATION: PHYSIOLOGICAL AND CHEMICAL OBSERVATIONS |
title_fullStr | THE CELL IN STARVATION: PHYSIOLOGICAL AND CHEMICAL OBSERVATIONS |
title_full_unstemmed | THE CELL IN STARVATION: PHYSIOLOGICAL AND CHEMICAL OBSERVATIONS |
title_short | THE CELL IN STARVATION: PHYSIOLOGICAL AND CHEMICAL OBSERVATIONS |
title_sort | cell in starvation: physiological and chemical observations |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2224133/ https://www.ncbi.nlm.nih.gov/pubmed/13481026 |
work_keys_str_mv | AT cohenadolphi thecellinstarvationphysiologicalandchemicalobservations AT cohenadolphi cellinstarvationphysiologicalandchemicalobservations |