Cargando…

Structure of Staphylococcus aureus guanylate monophosphate kinase

Nucleotide monophosphate kinases (NMPKs) are potential antimicrobial drug targets owing to their role in supplying DNA and RNA precursors. The present work reports the crystal structure of Staphylococcus aureus guanylate monophosphate kinase (SaGMK) at 1.9 Å resolution. The structure shows that unli...

Descripción completa

Detalles Bibliográficos
Autores principales:	El Omari, Kamel, Dhaliwal, Balvinder, Lockyer, Michael, Charles, Ian, Hawkins, Alastair R., Stammers, David K.
Formato:	Texto
Lenguaje:	English
Publicado:	International Union of Crystallography 2006
Materias:	Protein Structure Communications
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2225188/ https://www.ncbi.nlm.nih.gov/pubmed/17012781 http://dx.doi.org/10.1107/S174430910603613X

Ejemplares similares

Structure of Staphylococcus aureus cytidine monophosphate kinase in complex with cytidine 5′-monophosphate
por: Dhaliwal, Balvinder, et al.
Publicado: (2006)

Specificity of Staphyloferrin B Recognition by the SirA Receptor from Staphylococcus aureus
por: Grigg, Jason C., et al.
Publicado: (2010)

Structure-guided design and functional characterization of an artificial red light–regulated guanylate/adenylate cyclase for optogenetic applications
por: Etzl, Stefan, et al.
Publicado: (2018)

Structure-Function Analysis of the C3 Binding Region of Staphylococcus aureus Immune Subversion Protein Sbi
por: Upadhyay, Abhishek, et al.
Publicado: (2008)

Evidence for Steric Regulation of Fibrinogen Binding to Staphylococcus aureus Fibronectin-binding Protein A (FnBPA)
por: Stemberk, Vaclav, et al.
Publicado: (2014)

Crystal Structure of Staphylococcus aureus Metallopeptidase (Sapep) Reveals Large Domain Motions between the Manganese-bound and Apo-states
por: Girish, Tavarekere S., et al.
Publicado: (2010)

Structural basis for the glycosyltransferase activity of the Salmonella effector SseK3
por: Esposito, Diego, et al.
Publicado: (2018)

Structure of Pseudomonas aeruginosa inosine 5′-monophosphate dehydrogenase
por: Rao, Vincenzo A., et al.
Publicado: (2013)

Development of an HPLC-based guanosine monophosphate kinase assay and application to Plasmodium vivax guanylate kinase
por: Pedro, Liliana, et al.
Publicado: (2019)

Structural and functional characterization of the Mycobacterium tuberculosis uridine monophosphate kinase: insights into the allosteric regulation(†)
por: Labesse, Gilles, et al.
Publicado: (2011)

A range of C∊3–C∊4 interdomain angles in IgE Fc accommodate binding to its receptor CD23
por: Dhaliwal, Balvinder, et al.
Publicado: (2014)

Structure of the Nuclear Factor κB-inducing Kinase (NIK) Kinase Domain Reveals a Constitutively Active Conformation
por: Liu, Jinsong, et al.
Publicado: (2012)

Structural and biochemical characteristics of two Staphylococcus epidermidis RNase J paralogs RNase J1 and RNase J2
por: Raj, Rishi, et al.
Publicado: (2021)

Structural Basis for the Regulation of Protein Kinase A by Activation Loop Phosphorylation
por: Steichen, Jon M., et al.
Publicado: (2012)

The crystal structure of mammalian inositol 1,3,4,5,6-pentakisphosphate 2-kinase reveals a new zinc-binding site and key features for protein function
por: Franco-Echevarría, Elsa, et al.
Publicado: (2017)

Structural, Biochemical, and Biophysical Characterization of Idelalisib Binding to Phosphoinositide 3-Kinase δ
por: Somoza, John R., et al.
Publicado: (2015)

A model for 3-methyladenine recognition by 3-methyladenine DNA glycosylase I (TAG) from Staphylococcus aureus
por: Zhu, Xiaofeng, et al.
Publicado: (2012)

An Undecided Coiled Coil: THE LEUCINE ZIPPER OF Nek2 KINASE EXHIBITS ATYPICAL CONFORMATIONAL EXCHANGE DYNAMICS
por: Croasdale, Rebecca, et al.
Publicado: (2011)

Sensing Domain Dynamics in Protein Kinase A-Iα Complexes by Solution X-ray Scattering
por: Cheng, Cecilia Y., et al.
Publicado: (2009)

Mechanism of vaccinia viral protein B14–mediated inhibition of IκB kinase β activation
por: Tang, Qingyu, et al.
Publicado: (2018)

X-ray crystallographic studies reveal that the incorporation of spacer groups in carbonic anhydrase inhibitors causes alternate binding modes
por: Fisher, S. Zoë, et al.
Publicado: (2006)

High-resolution complex of papain with remnants of a cysteine protease inhibitor derived from Trypanosoma brucei
por: Alphey, Magnus S., et al.
Publicado: (2006)

Trypanosoma brucei UDP-galactose-4′-epimerase in ternary complex with NAD(+) and the substrate analogue UDP-4-deoxy-4-fluoro-α-d-galactose
por: Alphey, Magnus S., et al.
Publicado: (2006)

Structure of Bacillus halmapalus α-amylase crystallized with and without the substrate analogue acarbose and maltose
por: Lyhne-Iversen, Louise, et al.
Publicado: (2006)

Structure of the heterotrimeric PCNA from Sulfolobus solfataricus
por: Williams, Gareth J., et al.
Publicado: (2006)

Purification, crystallization and preliminary X-ray study of the fungal laccase from Cerrena maxima
por: Lyashenko, Andrey V., et al.
Publicado: (2006)

Fortuitous structure determination of ‘as-isolated’ Escherichia coli bacterioferritin in a novel crystal form
por: van Eerde, André, et al.
Publicado: (2006)

The nucleotide-binding site of Aquifex aeolicus LpxC
por: Buetow, Lori, et al.
Publicado: (2006)

Structure of a SARS coronavirus-derived peptide bound to the human major histocompatibility complex class I molecule HLA-B*1501
por: Røder, Gustav, et al.
Publicado: (2008)

Structure of HsaD, a steroid-degrading hydrolase, from Mycobacterium tuberculosis
por: Lack, Nathan, et al.
Publicado: (2007)

Structure of mouse ADP-ribosylhydrolase 3 (mARH3)
por: Mueller-Dieckmann, Christoph, et al.
Publicado: (2008)

Structure of the catalytic domain of Streptococcus pneumoniae sialidase NanA
por: Xu, Guogang, et al.
Publicado: (2008)

Structure of the T109S mutant of Escherichia coli dihydroorotase complexed with the inhibitor 5-fluoroorotate: catalytic activity is reflected by the crystal form
por: Lee, Mihwa, et al.
Publicado: (2007)

Structure of 5-formyltetrahydrofolate cyclo-ligase from Bacillus anthracis (BA4489)
por: Meier, Christoph, et al.
Publicado: (2007)

Monellin (MNEI) at 1.15 Å resolution
por: Hobbs, J. R., et al.
Publicado: (2007)

Structure of a xenon derivative of Escherichia coli copper amine oxidase: confirmation of the proposed oxygen-entry pathway
por: Pirrat, Pascale, et al.
Publicado: (2008)

Purification, crystallization and X-ray structures of the two manganese superoxide dismutases from Caenorhabditis elegans
por: Trinh, Chi H., et al.
Publicado: (2008)

Structure of the SARS coronavirus main proteinase as an active C(2) crystallographic dimer
por: Xu, Ting, et al.
Publicado: (2005)

Substrate binding induces structural changes in cytochrome P450cam
por: Sakurai, Keisuke, et al.
Publicado: (2009)

Crystal Structures of Human Choline Kinase Isoforms in Complex with Hemicholinium-3: SINGLE AMINO ACID NEAR THE ACTIVE SITE INFLUENCES INHIBITOR SENSITIVITY
por: Hong, Bum Soo, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_ccf2fsbm7hcc5b7ckuof6hotri