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Plasmid-based genetic modification of human bone marrow-derived stromal cells: analysis of cell survival and transgene expression after transplantation in rat spinal cord

BACKGROUND: Bone marrow-derived stromal cells (MSC) are attractive targets for ex vivo cell and gene therapy. In this context, we investigated the feasibility of a plasmid-based strategy for genetic modification of human (h)MSC with enhanced green fluorescent protein (EGFP) and neurotrophin (NT)3. T...

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Detalles Bibliográficos
Autores principales:	Ronsyn, Mark W, Daans, Jasmijn, Spaepen, Gie, Chatterjee, Shyama, Vermeulen, Katrien, D'Haese, Patrick, Van Tendeloo, Viggo FI, Van Marck, Eric, Ysebaert, Dirk, Berneman, Zwi N, Jorens, Philippe G, Ponsaerts, Peter
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2007
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2225398/ https://www.ncbi.nlm.nih.gov/pubmed/18078525 http://dx.doi.org/10.1186/1472-6750-7-90

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