DNA-PK contributes to the phosphorylation of AIRE: Importance in transcriptional activity

The autoimmune regulator (AIRE) protein is a key mediator of the central tolerance for tissue specific antigens and is involved in transcriptional control of many antigens in thymic medullary epithelial cells (mTEC). Mutations in the AIRE gene cause a rare disease named autoimmune polyendocrinopathy...

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Detalles Bibliográficos
Autores principales: Liiv, Ingrid, Rebane, Ana, Org, Tõnis, Saare, Mario, Maslovskaja, Julia, Kisand, Kai, Juronen, Erkki, Valmu, Leena, Bottomley, Matthew James, Kalkkinen, Nisse, Peterson, Pärt
Formato: Texto
Lenguaje:English
Publicado: Elsevier Pub. Co 2008
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2225445/
https://www.ncbi.nlm.nih.gov/pubmed/17997173
http://dx.doi.org/10.1016/j.bbamcr.2007.09.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2225445/
https://www.ncbi.nlm.nih.gov/pubmed/17997173
http://dx.doi.org/10.1016/j.bbamcr.2007.09.003

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