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DNA-PK contributes to the phosphorylation of AIRE: Importance in transcriptional activity
The autoimmune regulator (AIRE) protein is a key mediator of the central tolerance for tissue specific antigens and is involved in transcriptional control of many antigens in thymic medullary epithelial cells (mTEC). Mutations in the AIRE gene cause a rare disease named autoimmune polyendocrinopathy...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier Pub. Co
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2225445/ https://www.ncbi.nlm.nih.gov/pubmed/17997173 http://dx.doi.org/10.1016/j.bbamcr.2007.09.003 |