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Transcription-Dependent Gene Looping of the HIV-1 Provirus Is Dictated by Recognition of Pre-mRNA Processing Signals

HIV-1 provirus, either as a chromosomal integrant or as an episomal plasmid in HeLa cells, forms a transcription-dependent gene loop structure between the 5′LTR promoter and 3′LTR poly(A) signal. Flavopiridol-mediated inhibition of RNA polymerase II elongation blocks 5′ to 3′LTR juxtaposition, indic...

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Detalles Bibliográficos
Autores principales:	Perkins, Kelly J., Lusic, Marina, Mitar, Ivonne, Giacca, Mauro, Proudfoot, Nick J.
Formato:	Texto
Lenguaje:	English
Publicado:	Cell Press 2008
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2225447/ https://www.ncbi.nlm.nih.gov/pubmed/18206969 http://dx.doi.org/10.1016/j.molcel.2007.11.030

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