Cargando…
Divalent Cation Selectivity Is a Function of Gating in Native and Recombinant Cyclic Nucleotide–gated Ion Channels from Retinal Photoreceptors
The selectivity of Ca(2+) over Na(+) is ∼3.3-fold larger in cGMP-gated channels of cone photoreceptors than in those of rods when measured under saturating cGMP concentrations, where the probability of channel opening is 85–90%. Under physiological conditions, however, the probability of opening of...
Autores principales: | Hackos, David H., Korenbrot, Juan I. |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1999
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2225600/ https://www.ncbi.nlm.nih.gov/pubmed/10352032 |
Ejemplares similares
-
Calcium Modulation of Ligand Affinity in the Cyclic GMP–gated Ion Channels of Cone Photoreceptors
por: Hackos, David H., et al.
Publicado: (1997) -
The gating mechanism in cyclic nucleotide-gated ion channels
por: Mazzolini, Monica, et al.
Publicado: (2018) -
Voltage-dependence of Ion Permeation in Cyclic GMP–gated Ion Channels Is Optimized for Cell Function in Rod and Cone Photoreceptors
por: Ohyama, Tsuyoshi, et al.
Publicado: (2002) -
Interactions between divalent cations and the gating machinery of cyclic GMP-activated channels in salamander retinal rods
Publicado: (1993) -
Fraction of the Dark Current Carried by Ca(2+) through Cgmp-Gated Ion Channels of Intact Rod and Cone Photoreceptors
por: Ohyama, Tsuyoshi, et al.
Publicado: (2000)