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K(+) Occupancy of the N-Methyl-d-Aspartate Receptor Channel Probed by Mg(2+) Block

The single-channel kinetics of extracellular Mg(2+) block was used to probe K(+) binding sites in the permeation pathway of rat recombinant NR1/NR2B NMDA receptor channels. K(+) binds to three sites: two that are external and one that is internal to the site of Mg(2+) block. The internal site is ∼0....

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Detalles Bibliográficos
Autores principales: Zhu, Yongling, Auerbach, Anthony
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2225615/
https://www.ncbi.nlm.nih.gov/pubmed/11222631