Cargando…
Osmometrically Determined Characteristics of the Cell Membrane of Squid and Lobster Giant Axons
Lobster and squid giant nerve fibers respond differently when subjected to osmotic challenges. The axons proper, as distinct from the total (fiber) complex formed by the axon and connective sheath, both behave as "fast" osmometers for changes in the concentration of NaCl, but the maximum d...
Autores principales: | , , , |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1966
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2225644/ https://www.ncbi.nlm.nih.gov/pubmed/11526838 |
_version_ | 1782149674542563328 |
---|---|
author | Freeman, Alan R. Reuben, John P. Brandt, Philip W. Grundfest, Harry |
author_facet | Freeman, Alan R. Reuben, John P. Brandt, Philip W. Grundfest, Harry |
author_sort | Freeman, Alan R. |
collection | PubMed |
description | Lobster and squid giant nerve fibers respond differently when subjected to osmotic challenges. The axons proper, as distinct from the total (fiber) complex formed by the axon and connective sheath, both behave as "fast" osmometers for changes in the concentration of NaCl, but the maximum degree of swelling in hyposmotic media is by about 60% in lobster and only by 20% in squid. The relative volume intercepts of the van't Hoff relation are about 0.2 for lobster and 0.4 for squid. The sheaths of both axons undergo only small, apparently passive changes in volume. Lobster axons are permeable to Cl, but squid axons are impermeable to this anion. Lobster axons are also permeable to glycerol. The implications of the data as to the nature of volume regulation of cells are discussed. |
format | Text |
id | pubmed-2225644 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1966 |
publisher | The Rockefeller University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-22256442008-04-23 Osmometrically Determined Characteristics of the Cell Membrane of Squid and Lobster Giant Axons Freeman, Alan R. Reuben, John P. Brandt, Philip W. Grundfest, Harry J Gen Physiol Article Lobster and squid giant nerve fibers respond differently when subjected to osmotic challenges. The axons proper, as distinct from the total (fiber) complex formed by the axon and connective sheath, both behave as "fast" osmometers for changes in the concentration of NaCl, but the maximum degree of swelling in hyposmotic media is by about 60% in lobster and only by 20% in squid. The relative volume intercepts of the van't Hoff relation are about 0.2 for lobster and 0.4 for squid. The sheaths of both axons undergo only small, apparently passive changes in volume. Lobster axons are permeable to Cl, but squid axons are impermeable to this anion. Lobster axons are also permeable to glycerol. The implications of the data as to the nature of volume regulation of cells are discussed. The Rockefeller University Press 1966-11-01 /pmc/articles/PMC2225644/ /pubmed/11526838 Text en Copyright © 1967 by The Rockefeller University Press This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/). |
spellingShingle | Article Freeman, Alan R. Reuben, John P. Brandt, Philip W. Grundfest, Harry Osmometrically Determined Characteristics of the Cell Membrane of Squid and Lobster Giant Axons |
title | Osmometrically Determined Characteristics of the Cell Membrane of Squid and Lobster Giant Axons |
title_full | Osmometrically Determined Characteristics of the Cell Membrane of Squid and Lobster Giant Axons |
title_fullStr | Osmometrically Determined Characteristics of the Cell Membrane of Squid and Lobster Giant Axons |
title_full_unstemmed | Osmometrically Determined Characteristics of the Cell Membrane of Squid and Lobster Giant Axons |
title_short | Osmometrically Determined Characteristics of the Cell Membrane of Squid and Lobster Giant Axons |
title_sort | osmometrically determined characteristics of the cell membrane of squid and lobster giant axons |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2225644/ https://www.ncbi.nlm.nih.gov/pubmed/11526838 |
work_keys_str_mv | AT freemanalanr osmometricallydeterminedcharacteristicsofthecellmembraneofsquidandlobstergiantaxons AT reubenjohnp osmometricallydeterminedcharacteristicsofthecellmembraneofsquidandlobstergiantaxons AT brandtphilipw osmometricallydeterminedcharacteristicsofthecellmembraneofsquidandlobstergiantaxons AT grundfestharry osmometricallydeterminedcharacteristicsofthecellmembraneofsquidandlobstergiantaxons |