Surface Density of Calcium Ions and Calcium Spikes in the Barnacle Muscle Fiber Membrane

The effects of various divalent cations in the external solution upon the Ca spike of the barnacle muscle fiber membrane were studied using intracellular recording and polarizing techniques. Analysis of the maximum rate of rise of the spike potential indicates that different species of divalent cati...

Descripción completa

Detalles Bibliográficos
Autores principales: Hagiwara, Susumu, Takahashi, Kunitaro
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1967
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2225678/
https://www.ncbi.nlm.nih.gov/pubmed/11526848
_version_ 1782149682460360704
author Hagiwara, Susumu
Takahashi, Kunitaro
author_facet Hagiwara, Susumu
Takahashi, Kunitaro
author_sort Hagiwara, Susumu
collection PubMed
description The effects of various divalent cations in the external solution upon the Ca spike of the barnacle muscle fiber membrane were studied using intracellular recording and polarizing techniques. Analysis of the maximum rate of rise of the spike potential indicates that different species of divalent cations bind the same membrane sites competitively with different dissociation constants. The overshoot of the spike potential is determined by the density of Ca (Sr) ions in the membrane sites while the threshold membrane potential for spike initiation depends on the total density of divalent cations. The order of binding among different divalent and trivalent cations is the following: La(+++), UO(2) (++) > Zn(++), Co(++), Fe(++) > Mn(++) > Ni(++) > Ca(++) > Mg(++), Sr(++)
format Text
id pubmed-2225678
institution National Center for Biotechnology Information
language English
publishDate 1967
publisher The Rockefeller University Press
record_format MEDLINE/PubMed
spelling pubmed-22256782008-04-23 Surface Density of Calcium Ions and Calcium Spikes in the Barnacle Muscle Fiber Membrane Hagiwara, Susumu Takahashi, Kunitaro J Gen Physiol Article The effects of various divalent cations in the external solution upon the Ca spike of the barnacle muscle fiber membrane were studied using intracellular recording and polarizing techniques. Analysis of the maximum rate of rise of the spike potential indicates that different species of divalent cations bind the same membrane sites competitively with different dissociation constants. The overshoot of the spike potential is determined by the density of Ca (Sr) ions in the membrane sites while the threshold membrane potential for spike initiation depends on the total density of divalent cations. The order of binding among different divalent and trivalent cations is the following: La(+++), UO(2) (++) > Zn(++), Co(++), Fe(++) > Mn(++) > Ni(++) > Ca(++) > Mg(++), Sr(++) The Rockefeller University Press 1967-01-01 /pmc/articles/PMC2225678/ /pubmed/11526848 Text en Copyright © 1967 by The Rockefeller University Press This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Hagiwara, Susumu
Takahashi, Kunitaro
Surface Density of Calcium Ions and Calcium Spikes in the Barnacle Muscle Fiber Membrane
title Surface Density of Calcium Ions and Calcium Spikes in the Barnacle Muscle Fiber Membrane
title_full Surface Density of Calcium Ions and Calcium Spikes in the Barnacle Muscle Fiber Membrane
title_fullStr Surface Density of Calcium Ions and Calcium Spikes in the Barnacle Muscle Fiber Membrane
title_full_unstemmed Surface Density of Calcium Ions and Calcium Spikes in the Barnacle Muscle Fiber Membrane
title_short Surface Density of Calcium Ions and Calcium Spikes in the Barnacle Muscle Fiber Membrane
title_sort surface density of calcium ions and calcium spikes in the barnacle muscle fiber membrane
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2225678/
https://www.ncbi.nlm.nih.gov/pubmed/11526848
work_keys_str_mv AT hagiwarasusumu surfacedensityofcalciumionsandcalciumspikesinthebarnaclemusclefibermembrane
AT takahashikunitaro surfacedensityofcalciumionsandcalciumspikesinthebarnaclemusclefibermembrane

Ejemplares similares