Cation Movements in the High Sodium Erythrocyte of the Cat

The uptake of (42)K and (24)Na by cat erythrocytes was investigated. Under steady-state conditions, the nontransient component of (42)K influx was found to be 0.18 ± 0.01 meq/liter RBC/hr and insensitive to ouabain (100 µM); the corresponding value for (24)Na was 17 ± meq/liter RBC/hr. A study was m...

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Detalles Bibliográficos
Autores principales: Sha'afi, R. I., Lieb, W. R.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1967
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2225730/
https://www.ncbi.nlm.nih.gov/pubmed/6034766
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author Sha'afi, R. I.
Lieb, W. R.
author_facet Sha'afi, R. I.
Lieb, W. R.
author_sort Sha'afi, R. I.
collection PubMed
description The uptake of (42)K and (24)Na by cat erythrocytes was investigated. Under steady-state conditions, the nontransient component of (42)K influx was found to be 0.18 ± 0.01 meq/liter RBC/hr and insensitive to ouabain (100 µM); the corresponding value for (24)Na was 17 ± meq/liter RBC/hr. A study was made of the effects of anions upon cation movements in these and other mammalian red cells. Iodide was found to inhibit markedly (>50%) Na inward movements in cat and dog but not in the other erythrocytes. An increase (15–30%) in K uptake in the presence of iodide was noted in all the mammalian cells studied.
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spelling pubmed-22257302008-04-23 Cation Movements in the High Sodium Erythrocyte of the Cat Sha'afi, R. I. Lieb, W. R. J Gen Physiol Article The uptake of (42)K and (24)Na by cat erythrocytes was investigated. Under steady-state conditions, the nontransient component of (42)K influx was found to be 0.18 ± 0.01 meq/liter RBC/hr and insensitive to ouabain (100 µM); the corresponding value for (24)Na was 17 ± meq/liter RBC/hr. A study was made of the effects of anions upon cation movements in these and other mammalian red cells. Iodide was found to inhibit markedly (>50%) Na inward movements in cat and dog but not in the other erythrocytes. An increase (15–30%) in K uptake in the presence of iodide was noted in all the mammalian cells studied. The Rockefeller University Press 1967-07-01 /pmc/articles/PMC2225730/ /pubmed/6034766 Text en Copyright © 1967 by The Rockefeller University Press This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Sha'afi, R. I.
Lieb, W. R.
Cation Movements in the High Sodium Erythrocyte of the Cat
title Cation Movements in the High Sodium Erythrocyte of the Cat
title_full Cation Movements in the High Sodium Erythrocyte of the Cat
title_fullStr Cation Movements in the High Sodium Erythrocyte of the Cat
title_full_unstemmed Cation Movements in the High Sodium Erythrocyte of the Cat
title_short Cation Movements in the High Sodium Erythrocyte of the Cat
title_sort cation movements in the high sodium erythrocyte of the cat
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2225730/
https://www.ncbi.nlm.nih.gov/pubmed/6034766
work_keys_str_mv AT shaafiri cationmovementsinthehighsodiumerythrocyteofthecat
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