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Stimulation of the Labellar Sugar Receptor of the Fleshfly by Mono- and Disaccharides
Responses of the labellar sugar receptor of the fleshfly, Boettcherisca peregrina, were studied over a wide range of concentrations of several sugars (sucrose, maltose, glucose, fructose, and mannose) in single solutions and in mixtures. The results suggest (a) that the receptor sites are not comple...
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Formato: | Texto |
Lenguaje: | English |
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The Rockefeller University Press
1968
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2225817/ https://www.ncbi.nlm.nih.gov/pubmed/19873633 |
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author | Morita, Hiromichi Shiraishi, Akio |
author_facet | Morita, Hiromichi Shiraishi, Akio |
author_sort | Morita, Hiromichi |
collection | PubMed |
description | Responses of the labellar sugar receptor of the fleshfly, Boettcherisca peregrina, were studied over a wide range of concentrations of several sugars (sucrose, maltose, glucose, fructose, and mannose) in single solutions and in mixtures. The results suggest (a) that the receptor sites are not completely differentiated for glucose and for fructose combination, (b) that the receptor site is composed of two subunits. Such suggestions are based on the classical model, where the response is proportional to the number of the sites, two subunits of each site being simultaneously occupied with one molecule of disaccharides or two molecules of monosaccharides. It is shown, however, that an allosteric model gives a somewhat better interpretation of the experimental results. |
format | Text |
id | pubmed-2225817 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1968 |
publisher | The Rockefeller University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-22258172008-04-23 Stimulation of the Labellar Sugar Receptor of the Fleshfly by Mono- and Disaccharides Morita, Hiromichi Shiraishi, Akio J Gen Physiol Article Responses of the labellar sugar receptor of the fleshfly, Boettcherisca peregrina, were studied over a wide range of concentrations of several sugars (sucrose, maltose, glucose, fructose, and mannose) in single solutions and in mixtures. The results suggest (a) that the receptor sites are not completely differentiated for glucose and for fructose combination, (b) that the receptor site is composed of two subunits. Such suggestions are based on the classical model, where the response is proportional to the number of the sites, two subunits of each site being simultaneously occupied with one molecule of disaccharides or two molecules of monosaccharides. It is shown, however, that an allosteric model gives a somewhat better interpretation of the experimental results. The Rockefeller University Press 1968-09-01 /pmc/articles/PMC2225817/ /pubmed/19873633 Text en Copyright © 1968 by The Rockefeller University Press This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/). |
spellingShingle | Article Morita, Hiromichi Shiraishi, Akio Stimulation of the Labellar Sugar Receptor of the Fleshfly by Mono- and Disaccharides |
title | Stimulation of the Labellar Sugar Receptor of the Fleshfly by Mono- and Disaccharides |
title_full | Stimulation of the Labellar Sugar Receptor of the Fleshfly by Mono- and Disaccharides |
title_fullStr | Stimulation of the Labellar Sugar Receptor of the Fleshfly by Mono- and Disaccharides |
title_full_unstemmed | Stimulation of the Labellar Sugar Receptor of the Fleshfly by Mono- and Disaccharides |
title_short | Stimulation of the Labellar Sugar Receptor of the Fleshfly by Mono- and Disaccharides |
title_sort | stimulation of the labellar sugar receptor of the fleshfly by mono- and disaccharides |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2225817/ https://www.ncbi.nlm.nih.gov/pubmed/19873633 |
work_keys_str_mv | AT moritahiromichi stimulationofthelabellarsugarreceptorofthefleshflybymonoanddisaccharides AT shiraishiakio stimulationofthelabellarsugarreceptorofthefleshflybymonoanddisaccharides |