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Stimulation of the Labellar Sugar Receptor of the Fleshfly by Mono- and Disaccharides

Responses of the labellar sugar receptor of the fleshfly, Boettcherisca peregrina, were studied over a wide range of concentrations of several sugars (sucrose, maltose, glucose, fructose, and mannose) in single solutions and in mixtures. The results suggest (a) that the receptor sites are not comple...

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Detalles Bibliográficos
Autores principales: Morita, Hiromichi, Shiraishi, Akio
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1968
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2225830/
https://www.ncbi.nlm.nih.gov/pubmed/5687737
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author Morita, Hiromichi
Shiraishi, Akio
author_facet Morita, Hiromichi
Shiraishi, Akio
author_sort Morita, Hiromichi
collection PubMed
description Responses of the labellar sugar receptor of the fleshfly, Boettcherisca peregrina, were studied over a wide range of concentrations of several sugars (sucrose, maltose, glucose, fructose, and mannose) in single solutions and in mixtures. The results suggest (a) that the receptor sites are not completely differentiated for glucose and for fructose combination, (b) that the receptor site is composed of two subunits. Such suggestions are based on the classical model, where the response is proportional to the number of the sites, two subunits of each site being simultaneously occupied with one molecule of disaccharides or two molecules of monosaccharides. It is shown, however, that an allosteric model gives a somewhat better interpretation of the experimental results.
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spelling pubmed-22258302008-04-23 Stimulation of the Labellar Sugar Receptor of the Fleshfly by Mono- and Disaccharides Morita, Hiromichi Shiraishi, Akio J Gen Physiol Article Responses of the labellar sugar receptor of the fleshfly, Boettcherisca peregrina, were studied over a wide range of concentrations of several sugars (sucrose, maltose, glucose, fructose, and mannose) in single solutions and in mixtures. The results suggest (a) that the receptor sites are not completely differentiated for glucose and for fructose combination, (b) that the receptor site is composed of two subunits. Such suggestions are based on the classical model, where the response is proportional to the number of the sites, two subunits of each site being simultaneously occupied with one molecule of disaccharides or two molecules of monosaccharides. It is shown, however, that an allosteric model gives a somewhat better interpretation of the experimental results. The Rockefeller University Press 1968-10-01 /pmc/articles/PMC2225830/ /pubmed/5687737 Text en Copyright © 1968 by The Rockefeller University Press This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Morita, Hiromichi
Shiraishi, Akio
Stimulation of the Labellar Sugar Receptor of the Fleshfly by Mono- and Disaccharides
title Stimulation of the Labellar Sugar Receptor of the Fleshfly by Mono- and Disaccharides
title_full Stimulation of the Labellar Sugar Receptor of the Fleshfly by Mono- and Disaccharides
title_fullStr Stimulation of the Labellar Sugar Receptor of the Fleshfly by Mono- and Disaccharides
title_full_unstemmed Stimulation of the Labellar Sugar Receptor of the Fleshfly by Mono- and Disaccharides
title_short Stimulation of the Labellar Sugar Receptor of the Fleshfly by Mono- and Disaccharides
title_sort stimulation of the labellar sugar receptor of the fleshfly by mono- and disaccharides
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2225830/
https://www.ncbi.nlm.nih.gov/pubmed/5687737
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AT shiraishiakio stimulationofthelabellarsugarreceptorofthefleshflybymonoanddisaccharides