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Double-Stranded Polynucleotides as Interferon Inducers

A discussion of factors considered influential in making a polynucleotide an efficient inducer of interferon was presented. These factors were double-strandedness of the polynucleotides, the sugar moiety of the polynucleotides, thermal stability, resistance to enzymatic degradation, and molecular si...

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Detalles Bibliográficos
Autores principales: Field, A. K., Tytell, A. A., Lampson, G. P., Nemes, M. M., Hilleman, M. R.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1970
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2225865/
https://www.ncbi.nlm.nih.gov/pubmed/19873677
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author Field, A. K.
Tytell, A. A.
Lampson, G. P.
Nemes, M. M.
Hilleman, M. R.
author_facet Field, A. K.
Tytell, A. A.
Lampson, G. P.
Nemes, M. M.
Hilleman, M. R.
author_sort Field, A. K.
collection PubMed
description A discussion of factors considered influential in making a polynucleotide an efficient inducer of interferon was presented. These factors were double-strandedness of the polynucleotides, the sugar moiety of the polynucleotides, thermal stability, resistance to enzymatic degradation, and molecular size of the polynucloetides. Recent developments concerning interferon induction during virus infection were also discussed.
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spelling pubmed-22258652008-04-23 Double-Stranded Polynucleotides as Interferon Inducers Field, A. K. Tytell, A. A. Lampson, G. P. Nemes, M. M. Hilleman, M. R. J Gen Physiol Interferon Induction ⋅ II A discussion of factors considered influential in making a polynucleotide an efficient inducer of interferon was presented. These factors were double-strandedness of the polynucleotides, the sugar moiety of the polynucleotides, thermal stability, resistance to enzymatic degradation, and molecular size of the polynucloetides. Recent developments concerning interferon induction during virus infection were also discussed. The Rockefeller University Press 1970-07-01 /pmc/articles/PMC2225865/ /pubmed/19873677 Text en Copyright © 1970 by The Rockefeller University Press This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Interferon Induction ⋅ II
Field, A. K.
Tytell, A. A.
Lampson, G. P.
Nemes, M. M.
Hilleman, M. R.
Double-Stranded Polynucleotides as Interferon Inducers
title Double-Stranded Polynucleotides as Interferon Inducers
title_full Double-Stranded Polynucleotides as Interferon Inducers
title_fullStr Double-Stranded Polynucleotides as Interferon Inducers
title_full_unstemmed Double-Stranded Polynucleotides as Interferon Inducers
title_short Double-Stranded Polynucleotides as Interferon Inducers
title_sort double-stranded polynucleotides as interferon inducers
topic Interferon Induction ⋅ II
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2225865/
https://www.ncbi.nlm.nih.gov/pubmed/19873677
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