The Uptake of a Labeled Double-Stranded Polynucleotide by Cultured Rabbit Kidney Cells: An Electron Microscopic Study

Polyribocytidylate-(3)H-polyriboinosinate (rC-(3)H:rI) enters cultured rabbit kidney cells from the surrounding medium within ½ hr after exposure. Grains are found in the cytoplasm, nucleus, and nucleolus. At 2 hr, grains are localized predominantly over the nucleolar regions. Subsequently, the grai...

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Detalles Bibliográficos
Autores principales: Prose, Philip H., Friedman-Kien, Alvin, Vilček, Jan
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1970
Materias:
Interferon Induction ⋅ II
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2225873/
https://www.ncbi.nlm.nih.gov/pubmed/19873679
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author Prose, Philip H.
Friedman-Kien, Alvin
Vilček, Jan
author_facet Prose, Philip H.
Friedman-Kien, Alvin
Vilček, Jan
author_sort Prose, Philip H.
collection PubMed
description Polyribocytidylate-(3)H-polyriboinosinate (rC-(3)H:rI) enters cultured rabbit kidney cells from the surrounding medium within ½ hr after exposure. Grains are found in the cytoplasm, nucleus, and nucleolus. At 2 hr, grains are localized predominantly over the nucleolar regions. Subsequently, the grains in the nucleus become dispersed. A specific receptor site for the initiation of interferon production was not revealed.
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spelling pubmed-22258732008-04-23 The Uptake of a Labeled Double-Stranded Polynucleotide by Cultured Rabbit Kidney Cells: An Electron Microscopic Study Prose, Philip H. Friedman-Kien, Alvin Vilček, Jan J Gen Physiol Interferon Induction ⋅ II Polyribocytidylate-(3)H-polyriboinosinate (rC-(3)H:rI) enters cultured rabbit kidney cells from the surrounding medium within ½ hr after exposure. Grains are found in the cytoplasm, nucleus, and nucleolus. At 2 hr, grains are localized predominantly over the nucleolar regions. Subsequently, the grains in the nucleus become dispersed. A specific receptor site for the initiation of interferon production was not revealed. The Rockefeller University Press 1970-07-01 /pmc/articles/PMC2225873/ /pubmed/19873679 Text en Copyright © 1970 by The Rockefeller University Press This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Interferon Induction ⋅ II
Prose, Philip H.
Friedman-Kien, Alvin
Vilček, Jan
The Uptake of a Labeled Double-Stranded Polynucleotide by Cultured Rabbit Kidney Cells: An Electron Microscopic Study
title The Uptake of a Labeled Double-Stranded Polynucleotide by Cultured Rabbit Kidney Cells: An Electron Microscopic Study
title_full The Uptake of a Labeled Double-Stranded Polynucleotide by Cultured Rabbit Kidney Cells: An Electron Microscopic Study
title_fullStr The Uptake of a Labeled Double-Stranded Polynucleotide by Cultured Rabbit Kidney Cells: An Electron Microscopic Study
title_full_unstemmed The Uptake of a Labeled Double-Stranded Polynucleotide by Cultured Rabbit Kidney Cells: An Electron Microscopic Study
title_short The Uptake of a Labeled Double-Stranded Polynucleotide by Cultured Rabbit Kidney Cells: An Electron Microscopic Study
title_sort uptake of a labeled double-stranded polynucleotide by cultured rabbit kidney cells: an electron microscopic study
topic Interferon Induction ⋅ II
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2225873/
https://www.ncbi.nlm.nih.gov/pubmed/19873679
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