Ion Transport Through Excitability-Inducing Material (EIM) Channels in Lipid Bilayer Membranes

Two different methods were used to determine the relative permeability and the voltage-dependent conductance of several different cations in excitability-inducing material (EIM)-doped lipid bilayers. In one method, the conductances of individual channels were measured for Li, Na, K, Cs, NH(4), and C...

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Detalles Bibliográficos
Autores principales: Latorre, Ramon, Ehrenstein, Gerald, Lecar, Harold
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1972
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2226051/
https://www.ncbi.nlm.nih.gov/pubmed/5042024
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author Latorre, Ramon
Ehrenstein, Gerald
Lecar, Harold
author_facet Latorre, Ramon
Ehrenstein, Gerald
Lecar, Harold
author_sort Latorre, Ramon
collection PubMed
description Two different methods were used to determine the relative permeability and the voltage-dependent conductance of several different cations in excitability-inducing material (EIM)-doped lipid bilayers. In one method, the conductances of individual channels were measured for Li, Na, K, Cs, NH(4), and Ca, and in the other method biionic potentials of a membrane with many channels were measured for Li, Na, K, Cs, and Rb. The experimental results for the two methods are in agreement. The relative permeabilities are proportional to the ionic mobilities in free aqueous solution. The voltage dependence of the conductance is the same for all cations measured.
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spelling pubmed-22260512008-04-23 Ion Transport Through Excitability-Inducing Material (EIM) Channels in Lipid Bilayer Membranes Latorre, Ramon Ehrenstein, Gerald Lecar, Harold J Gen Physiol Article Two different methods were used to determine the relative permeability and the voltage-dependent conductance of several different cations in excitability-inducing material (EIM)-doped lipid bilayers. In one method, the conductances of individual channels were measured for Li, Na, K, Cs, NH(4), and Ca, and in the other method biionic potentials of a membrane with many channels were measured for Li, Na, K, Cs, and Rb. The experimental results for the two methods are in agreement. The relative permeabilities are proportional to the ionic mobilities in free aqueous solution. The voltage dependence of the conductance is the same for all cations measured. The Rockefeller University Press 1972-07-01 /pmc/articles/PMC2226051/ /pubmed/5042024 Text en Copyright © 1972 by The Rockefeller University Press This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Latorre, Ramon
Ehrenstein, Gerald
Lecar, Harold
Ion Transport Through Excitability-Inducing Material (EIM) Channels in Lipid Bilayer Membranes
title Ion Transport Through Excitability-Inducing Material (EIM) Channels in Lipid Bilayer Membranes
title_full Ion Transport Through Excitability-Inducing Material (EIM) Channels in Lipid Bilayer Membranes
title_fullStr Ion Transport Through Excitability-Inducing Material (EIM) Channels in Lipid Bilayer Membranes
title_full_unstemmed Ion Transport Through Excitability-Inducing Material (EIM) Channels in Lipid Bilayer Membranes
title_short Ion Transport Through Excitability-Inducing Material (EIM) Channels in Lipid Bilayer Membranes
title_sort ion transport through excitability-inducing material (eim) channels in lipid bilayer membranes
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2226051/
https://www.ncbi.nlm.nih.gov/pubmed/5042024
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