Voltage Clamp Experiments on Single Muscle Fibers of Rana pipiens

A voltage clamp for single muscle fibers has been developed. Stability of the system was achieved when an artificial node was created by enclosing a single muscle fiber in a petroleum jelly seal which served as an analogue of the myelin sheath. Typical voltage clamp records were obtained with large...

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Detalles Bibliográficos
Autor principal: Moore, L. E.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1972
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2226057/
https://www.ncbi.nlm.nih.gov/pubmed/4537778
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author Moore, L. E.
author_facet Moore, L. E.
author_sort Moore, L. E.
collection PubMed
description A voltage clamp for single muscle fibers has been developed. Stability of the system was achieved when an artificial node was created by enclosing a single muscle fiber in a petroleum jelly seal which served as an analogue of the myelin sheath. Typical voltage clamp records were obtained with large inward transient currents followed by a delayed rectification of the outward currents. These currents looked qualitatively similar when the transverse tubular system was destroyed. Errors in current measurement, especially those due to anomalous rectification, are discussed.
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spelling pubmed-22260572008-04-23 Voltage Clamp Experiments on Single Muscle Fibers of Rana pipiens Moore, L. E. J Gen Physiol Article A voltage clamp for single muscle fibers has been developed. Stability of the system was achieved when an artificial node was created by enclosing a single muscle fiber in a petroleum jelly seal which served as an analogue of the myelin sheath. Typical voltage clamp records were obtained with large inward transient currents followed by a delayed rectification of the outward currents. These currents looked qualitatively similar when the transverse tubular system was destroyed. Errors in current measurement, especially those due to anomalous rectification, are discussed. The Rockefeller University Press 1972-07-01 /pmc/articles/PMC2226057/ /pubmed/4537778 Text en Copyright © 1972 by The Rockefeller University Press This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Moore, L. E.
Voltage Clamp Experiments on Single Muscle Fibers of Rana pipiens
title Voltage Clamp Experiments on Single Muscle Fibers of Rana pipiens
title_full Voltage Clamp Experiments on Single Muscle Fibers of Rana pipiens
title_fullStr Voltage Clamp Experiments on Single Muscle Fibers of Rana pipiens
title_full_unstemmed Voltage Clamp Experiments on Single Muscle Fibers of Rana pipiens
title_short Voltage Clamp Experiments on Single Muscle Fibers of Rana pipiens
title_sort voltage clamp experiments on single muscle fibers of rana pipiens
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2226057/
https://www.ncbi.nlm.nih.gov/pubmed/4537778
work_keys_str_mv AT moorele voltageclampexperimentsonsinglemusclefibersofranapipiens

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