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Antagonistic Components of the Late Receptor Potential in the Barnacle Photoreceptor Arising from Different Stages of the Pigment Process

The late receptor potential (LRP) recorded in barnacle photoreceptor cells exhibits, at high light levels, a strong dependence on the color of the stimulus and of the preceding adaptation. Most strikingly, red illumination of a cell previously adapted to blue light results in a depolarization which...

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Autores principales: Hochstein, S., Minke, B., Hillman, P.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1973
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2226106/
https://www.ncbi.nlm.nih.gov/pubmed/4767023
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author Hochstein, S.
Minke, B.
Hillman, P.
author_facet Hochstein, S.
Minke, B.
Hillman, P.
author_sort Hochstein, S.
collection PubMed
description The late receptor potential (LRP) recorded in barnacle photoreceptor cells exhibits, at high light levels, a strong dependence on the color of the stimulus and of the preceding adaptation. Most strikingly, red illumination of a cell previously adapted to blue light results in a depolarization which may last for up to 30 min after the light goes off, while blue illumination of a cell previously adapted to red light cuts short this extended depolarization or prevents its induction by a closely following red light. Comparison of the action spectra for the stimulus-coincident LRP and for the extended depolarization and its curtailment with those previously measured for the early receptor potential (ERP) confirms that these phenomena derive from the same bi-stable pigment as the ERP. The stimulus-coincident response and the extended depolarization appear to arise from substantial activation of the stable 532 nm state of the pigment, while activation of the stable 495 state depresses or prevents the extended depolarization and probably also depresses the stimulus-coincident response. Since either process can precede the other, with mutually antagonistic effects, one is not simply the reversal of the other; they must be based on separate mechanisms. Furthermore, comparison with ERP kinetics shows that both processes involve mechanisms additional to the pigment changes, as seen in the ERP. A model is proposed and discussed for the LRP phenomena and their dependences on wavelength, intensity, and duration of illumination based on excitor-inhibitor interactions.
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spelling pubmed-22261062008-04-23 Antagonistic Components of the Late Receptor Potential in the Barnacle Photoreceptor Arising from Different Stages of the Pigment Process Hochstein, S. Minke, B. Hillman, P. J Gen Physiol Article The late receptor potential (LRP) recorded in barnacle photoreceptor cells exhibits, at high light levels, a strong dependence on the color of the stimulus and of the preceding adaptation. Most strikingly, red illumination of a cell previously adapted to blue light results in a depolarization which may last for up to 30 min after the light goes off, while blue illumination of a cell previously adapted to red light cuts short this extended depolarization or prevents its induction by a closely following red light. Comparison of the action spectra for the stimulus-coincident LRP and for the extended depolarization and its curtailment with those previously measured for the early receptor potential (ERP) confirms that these phenomena derive from the same bi-stable pigment as the ERP. The stimulus-coincident response and the extended depolarization appear to arise from substantial activation of the stable 532 nm state of the pigment, while activation of the stable 495 state depresses or prevents the extended depolarization and probably also depresses the stimulus-coincident response. Since either process can precede the other, with mutually antagonistic effects, one is not simply the reversal of the other; they must be based on separate mechanisms. Furthermore, comparison with ERP kinetics shows that both processes involve mechanisms additional to the pigment changes, as seen in the ERP. A model is proposed and discussed for the LRP phenomena and their dependences on wavelength, intensity, and duration of illumination based on excitor-inhibitor interactions. The Rockefeller University Press 1973-07-01 /pmc/articles/PMC2226106/ /pubmed/4767023 Text en Copyright © 1973 by The Rockefeller University Press This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Hochstein, S.
Minke, B.
Hillman, P.
Antagonistic Components of the Late Receptor Potential in the Barnacle Photoreceptor Arising from Different Stages of the Pigment Process
title Antagonistic Components of the Late Receptor Potential in the Barnacle Photoreceptor Arising from Different Stages of the Pigment Process
title_full Antagonistic Components of the Late Receptor Potential in the Barnacle Photoreceptor Arising from Different Stages of the Pigment Process
title_fullStr Antagonistic Components of the Late Receptor Potential in the Barnacle Photoreceptor Arising from Different Stages of the Pigment Process
title_full_unstemmed Antagonistic Components of the Late Receptor Potential in the Barnacle Photoreceptor Arising from Different Stages of the Pigment Process
title_short Antagonistic Components of the Late Receptor Potential in the Barnacle Photoreceptor Arising from Different Stages of the Pigment Process
title_sort antagonistic components of the late receptor potential in the barnacle photoreceptor arising from different stages of the pigment process
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2226106/
https://www.ncbi.nlm.nih.gov/pubmed/4767023
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