Cargando…
Mode of Action of Chronotropic Agents in Cardiac Purkinje Fibers : Does Epinephrine Act by Directly Modifying the External Surface Charge?
Hauswirth et al. (1968) proposed that epinephrine acts on i (K(K2)) by adding its own positive charge to the external membrane surface near the i (K(K2)) channel. This hypothesis was tested by using noncationic compounds, theophylline and R07-2956, which mimicked epinephrine's effects on pacema...
| Autor principal: | |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
1974
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2226176/ https://www.ncbi.nlm.nih.gov/pubmed/4370200 |