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Production and characterization of a recombinant anti-MUC1 scFv reactive with human carcinomas.

Recombinant single-chain fragments (scFv) of the murine anti-MUC1 monoclonal antibody C595 have been produced using the original hybridoma cells as a source of variable heavy (V(H))- and variable light (V(L))-chain-encoding antibody genes. The use of the polymerase chain reaction (PCR), bacteriophag...

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Detalles Bibliográficos
Autores principales: Denton, G., Sekowski, M., Spencer, D. I., Hughes, O. D., Murray, A., Denley, H., Tendler, S. J., Price, M. R.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1997
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2228010/
https://www.ncbi.nlm.nih.gov/pubmed/9303360