High-dose mitoxantrone with peripheral blood progenitor cell rescue: toxicity, pharmacokinetics and implications for dosage and schedule.

The optimal use of mitoxantrone (NOV) in the high-dose range requires elucidation of its maximum tolerated dose with peripheral blood progenitor cell (PBPC) support and the time interval needed between drug administration and PBPC reinfusion in order to avoid graft toxicity. The aims of this study w...

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Detalles Bibliográficos
Autores principales: Ballestrero, A., Ferrando, F., Garuti, A., Basta, P., Gonella, R., Esposito, M., Vannozzi, M. O., Sorice, G., Friedman, D., Puglisi, M., Brema, F., Mela, G. S., Sessarego, M., Patrone, F.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1997
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2228044/
https://www.ncbi.nlm.nih.gov/pubmed/9310249

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