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Expression of the DNA mismatch repair proteins hMLH1 and hPMS2 in normal human tissues.
hMLH1 and hPMS2 are part of the DNA mismatch repair complex. Mutations in these genes have been linked to hereditary non-polyposis colon cancer; they also occur in a variety of sporadic cancers. Western blot analysis and immunohistochemistry demonstrated that hMLH1 and hPMS2 are widely expressed nuc...
Autores principales: | Fink, D., Nebel, S., Aebi, S., Zheng, H., Kim, H. K., Christen, R. D., Howell, S. B. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
1997
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2228055/ https://www.ncbi.nlm.nih.gov/pubmed/9328148 |
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