Menadione-resistant Chinese hamster ovary cells have an increased capacity for glutathione synthesis.

A cell line (MRc40) resistant to the model quinone compound, menadione, has been isolated from a parental Chinese hamster ovary cell line (CHO-K1). The known relationship between menadione toxicity and glutathione (GSH) depletion led us to investigate whether the mechanism of resistance of MRc40 was...

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Detalles Bibliográficos
Autores principales: Vallis, K. A., Reglinski, J., Garner, M., Bridgeman, M. M., Wolf, C. R.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1997
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2228060/
https://www.ncbi.nlm.nih.gov/pubmed/9328145

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