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An experimental and mathematical model for the extravascular transport of a DNA intercalator in tumours.
A new in vitro model has been developed for investigating extravascular diffusion of therapeutic agents in tumour tissue. V79-171b or EMT6/Ak cells are grown on porous Teflon support membranes and submerged in a large reservoir of medium, to give diffusion-limited 'multicellular membranes'...
Autores principales: | Hicks, K. O., Ohms, S. J., van Zijl, P. L., Denny, W. A., Hunter, P. J., Wilson, W. R. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
1997
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2228074/ https://www.ncbi.nlm.nih.gov/pubmed/9328149 |
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