Deletion mapping and linkage analysis provide strong indication for the involvement of the human chromosome region 8p12-p22 in breast carcinogenesis.

We have identified a high frequency of loss of heterozygosity (LOH) on the human chromosome region 8p12-p22 in a panel of microdissected familial (86% LOH) and sporadic (74% LOH) breast tumours. The two most frequently deleted regions were defined around marker D8S133 and in a broader centromeric re...

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Detalles Bibliográficos
Autores principales: Seitz, S., Rohde, K., Bender, E., Nothnagel, A., Pidde, H., Ullrich, O. M., El-Zehairy, A., Haensch, W., Jandrig, B., Kölble, K., Schlag, P. M., Scherneck, S.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1997
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2228086/
https://www.ncbi.nlm.nih.gov/pubmed/9376278

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2228086/
https://www.ncbi.nlm.nih.gov/pubmed/9376278

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