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Highly sensitive and specific detection of P-glycoprotein function for haematological and solid tumour cells using a novel nucleic acid stain.
Progress in our understanding of the contribution of P-glycoprotein (P-gp)-mediated resistance to chemotherapy failure in haematological as well as solid tumours has been hampered by the lack of highly sensitive, reliable methods for the detection of P-gp function in fresh human tumour cells. The pr...
Autores principales: | Broxterman, H. J., Schuurhuis, G. J., Lankelma, J., Oberink, J. W., Eekman, C. A., Claessen, A. M., Hoekman, K., Poot, M., Pinedo, H. M. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
1997
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2228098/ https://www.ncbi.nlm.nih.gov/pubmed/9376262 |
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