Cargando…

Platinum-DNA adduct formation in leucocytes of children in relation to pharmacokinetics after cisplatin and carboplatin therapy.

Platinum (Pt)-DNA adducts were measured in peripheral blood leucocytes (PBLs) from 24 children with solid tumours after standard cisplatin and/or carboplatin treatment. The relationship between Pt-DNA adduct levels and pharmacokinetics of cisplatin and carboplatin was investigated. Adduct measuremen...

Descripción completa

Detalles Bibliográficos
Autores principales:	Peng, B., Tilby, M. J., English, M. W., Price, L., Pearson, A. D., Boddy, A. V., Newell, D. R.
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 1997
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2228168/ https://www.ncbi.nlm.nih.gov/pubmed/9400943

Ejemplares similares

Adaptive dosing and platinum–DNA adduct formation in children receiving high-dose carboplatin for the treatment of solid tumours
por: Veal, G J, et al.
Publicado: (2007)

Pharmacokinetically guided dosing of carboplatin and etoposide during peritoneal dialysis and haemodialysis.
por: English, M. W., et al.
Publicado: (1996)

Relationship between the exposure to cisplatin, DNA-adduct formation in leucocytes and tumour response in patients with solid tumours.
por: Schellens, J. H., et al.
Publicado: (1996)

Current sample handling methods for measurement of platinum-DNA adducts in leucocytes in man lead to discrepant results in DNA adduct levels and DNA repair.
por: Ma, J., et al.
Publicado: (1995)

Pharmacokinetics and metabolism of ifosfamide in relation to DNA damage assessed by the COMET assay in children with cancer
por: Willits, I, et al.
Publicado: (2005)

Immunocytochemical analysis of cisplatin-induced platinum-DNA adducts with double-fluorescence video microscopy.
por: Meijer, C., et al.
Publicado: (1997)

Cisplatin and carboplatin pharmacokinetics in a pediatric patient with hepatoblastoma receiving peritoneal dialysis
por: Nijstad, A. Laura, et al.
Publicado: (2020)

Dose-related nephrotoxicity of carboplatin in children
por: English, M W, et al.
Publicado: (1999)

Antitumor Activity of the Carboplatin-α-Cyclodextrin Adduct
por: Liu, Weiping, et al.
Publicado: (1997)

Hydrated electrons induce the formation of interstrand cross-links in DNA modified by cisplatin adducts
por: Behmand, B, et al.
Publicado: (2020)

Cisplatin-DNA adduct formation in patients treated with cisplatin-based chemoradiation: lack of correlation between normal tissues and primary tumor
por: Hoebers, F. J. P., et al.
Publicado: (2007)

A clinical and pharmacokinetic study of the combination of carboplatin and paclitaxel for epithelial ovarian cancer.
por: Siddiqui, N., et al.
Publicado: (1997)

Pharmacodynamics of cisplatin in human head and neck cancer: correlation between platinum content, DNA adduct levels and drug sensitivity in vitro and in vivo
por: Welters, M J P, et al.
Publicado: (1999)

Boosting cisplatin chemotherapy by nanomotor-enhanced tumor penetration and DNA adducts formation
por: Xu, Lihua, et al.
Publicado: (2022)

Estimation of renal function and its potential impact on carboplatin dosing in children with cancer
por: Chinnaswamy, G, et al.
Publicado: (2008)

Monofunctional and Interstrand DNA Adducts of Platinum(II) Complexes
por: Brabec, Viktor, et al.
Publicado: (1994)

Schedule-dependent response of neuroblastoma cell lines to combinations of etoposide and cisplatin
por: Meczes, E L, et al.
Publicado: (2002)

Formation and repair kinetics of Pt-(GpG) DNA adducts in extracted circulating tumour cells and response to platinum treatment
por: Nel, I, et al.
Publicado: (2013)

Structural basis for the sequence-dependent effects of platinum–DNA adducts
por: Ramachandran, Srinivas, et al.
Publicado: (2009)

Cisplatin/carboplatin cross-resistance in ovarian cancer.
por: Gore, M. E., et al.
Publicado: (1989)

Antitumor Trans Platinum Adducts of GMP and AMP
por: Liu, Yangzhong, et al.
Publicado: (2000)

Cisplatin adducts of DNA as precursors for nanostructured catalyst materials
por: Englert, Klaudia, et al.
Publicado: (2020)

Evaluation of novel ammine/amine platinum (IV) dicarboxylates in L1210 murine leukaemia cells sensitive and resistant to cisplatin, tetraplatin or carboplatin.
por: Orr, R. M., et al.
Publicado: (1994)

Relationships between DNA adduct formation and carcinogenesis.
por: Swenberg, J A, et al.
Publicado: (1985)

Cisplatin and platinum pharmacokinetics during hyperthermic isolated limb perfusion for human tumours of the extremities.
por: Guchelaar, H. J., et al.
Publicado: (1992)

Detection and Characterization of Single Cisplatin Adducts on DNA by Nanopore Sequencing
por: Zhao, Xinjia, et al.
Publicado: (2021)

A phase I and pharmacokinetic study of indisulam in combination with carboplatin
por: Dittrich, C, et al.
Publicado: (2007)

Nitropyrene: DNA binding and adduct formation in respiratory tissues.
por: Jackson, M A, et al.
Publicado: (1985)

Formation and persistence of arylamine DNA adducts in vivo.
por: Beland, F A, et al.
Publicado: (1985)

A Phase I clinical study of cisplatin-incorporated polymeric micelles (NC-6004) in patients with solid tumours
por: Plummer, R, et al.
Publicado: (2011)

A study of the feasibility and accuracy of pharmacokinetically guided etoposide dosing in children.
por: Lowis, S. P., et al.
Publicado: (1998)

A phase I study in paediatric patients to evaluate the safety and pharmacokinetics of SPI-77, a liposome encapsulated formulation of cisplatin
por: Veal, G J, et al.
Publicado: (2001)

Combination chemotherapy with taxane and platinum in patients with salivary gland carcinoma: a retrospective study of docetaxel plus cisplatin and paclitaxel plus carboplatin
por: Onaga, Ryutaro, et al.
Publicado: (2023)

Oxaliplatin-DNA adduct formation in white blood cells of cancer patients
por: Pieck, A C, et al.
Publicado: (2008)

Advanced seminoma: treatment with cis-platinum-based combination chemotherapy or carboplatin (JM8).
por: Peckham, M. J., et al.
Publicado: (1985)

Evaluation of pharmacokinetics and safety of cetuximab with cisplatin/carboplatin in patients with advanced solid tumor: Result from phase II studies
por: Perez, Raymond P., et al.
Publicado: (2019)

Haematological toxicity of carboplatin and cisplatin combined with whole body hyperthermia in rats.
por: Ohno, S., et al.
Publicado: (1993)

Risk of thromboembolism in cisplatin versus carboplatin-treated patients with lung cancer
por: Kim, Eric S., et al.
Publicado: (2017)

Activation of dihaloalkanes by glutathione conjugation and formation of DNA adducts.
por: Guengerich, F P, et al.
Publicado: (1987)

Successful Treatment with Pemetrexed, Carboplatin, and Bevacizumab for Platinum-Resistant Adenocarcinoma of the Lung
por: Wada, Sae, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_670ksdoql0s3l11a3r1emao47f