Germline BRCA2 mutations in men with breast cancer.

Breast cancer in men is rare and is clearly due in some cases to an inherited predisposition. A total of 28 male breast cancer patients were tested for BRCA2 mutations; two frameshifts and one putative missense mutation were identified. One of the frameshifts was detected in the same position as a m...

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Detalles Bibliográficos
Autores principales: Mavraki, E., Gray, I. C., Bishop, D. T., Spurr, N. K.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1997
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2228180/
https://www.ncbi.nlm.nih.gov/pubmed/9400938
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author Mavraki, E.
Gray, I. C.
Bishop, D. T.
Spurr, N. K.
author_facet Mavraki, E.
Gray, I. C.
Bishop, D. T.
Spurr, N. K.
author_sort Mavraki, E.
collection PubMed
description Breast cancer in men is rare and is clearly due in some cases to an inherited predisposition. A total of 28 male breast cancer patients were tested for BRCA2 mutations; two frameshifts and one putative missense mutation were identified. One of the frameshifts was detected in the same position as a mutation estimated to be responsible for 40% of all male breast cancer cases in Iceland. IMAGES:
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spelling pubmed-22281802009-09-10 Germline BRCA2 mutations in men with breast cancer. Mavraki, E. Gray, I. C. Bishop, D. T. Spurr, N. K. Br J Cancer Research Article Breast cancer in men is rare and is clearly due in some cases to an inherited predisposition. A total of 28 male breast cancer patients were tested for BRCA2 mutations; two frameshifts and one putative missense mutation were identified. One of the frameshifts was detected in the same position as a mutation estimated to be responsible for 40% of all male breast cancer cases in Iceland. IMAGES: Nature Publishing Group 1997 /pmc/articles/PMC2228180/ /pubmed/9400938 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Research Article
Mavraki, E.
Gray, I. C.
Bishop, D. T.
Spurr, N. K.
Germline BRCA2 mutations in men with breast cancer.
title Germline BRCA2 mutations in men with breast cancer.
title_full Germline BRCA2 mutations in men with breast cancer.
title_fullStr Germline BRCA2 mutations in men with breast cancer.
title_full_unstemmed Germline BRCA2 mutations in men with breast cancer.
title_short Germline BRCA2 mutations in men with breast cancer.
title_sort germline brca2 mutations in men with breast cancer.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2228180/
https://www.ncbi.nlm.nih.gov/pubmed/9400938
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AT spurrnk germlinebrca2mutationsinmenwithbreastcancer

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