Up-regulation of p21WAF1 expression in myeloid cells is activated by the protein kinase C pathway.

Phorbol-12-myristate-13-acetate (PMA) induces p21WAF-1 expression in human myeloid leukaemic HL-60 cells. We show that this induction is specifically mediated by protein kinase C (PKC). In addition, the PKC inhibitor Ro 31-8220 with predominant PKC-alpha isoform specificity almost completely inhibit...

Descripción completa

Detalles Bibliográficos
Autores principales: Schwaller, J., Peters, U. R., Pabst, T., Niklaus, G., Macfarlane, D. E., Fey, M. F., Tobler, A.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1997
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2228197/
https://www.ncbi.nlm.nih.gov/pubmed/9413940

Ejemplares similares

Ejemplares similares