Preliminary results of the use of intraperitoneal carbon-adsorbed mitomycin C in intra-abdominal malignancy.

Eleven patients suffering from intra-abdominal malignancy were treated with various doses of intraperitoneal mitomycin C adsorbed onto activated carbon particles. Seven of the patients underwent resection of their primary gastric tumour and all developed potentially life-threatening severe complicat...

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Autores principales: Ubhi, S. S., McCulloch, P., Veitch, P. S.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1997
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2228208/
https://www.ncbi.nlm.nih.gov/pubmed/9413960
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author Ubhi, S. S.
McCulloch, P.
Veitch, P. S.
author_facet Ubhi, S. S.
McCulloch, P.
Veitch, P. S.
author_sort Ubhi, S. S.
collection PubMed
description Eleven patients suffering from intra-abdominal malignancy were treated with various doses of intraperitoneal mitomycin C adsorbed onto activated carbon particles. Seven of the patients underwent resection of their primary gastric tumour and all developed potentially life-threatening severe complications that proved to be fatal in four patients. The pattern of complications seen in these patients was unusual in patients undergoing gastrectomy and must be presumed to be secondary to the intraperitoneal mitomycin C. Intraperitoneal mitomycin C at a dose of 25 mg and 50 mg in the presence of an anastomosis or other suture line does not appear to be safe.
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spelling pubmed-22282082009-09-10 Preliminary results of the use of intraperitoneal carbon-adsorbed mitomycin C in intra-abdominal malignancy. Ubhi, S. S. McCulloch, P. Veitch, P. S. Br J Cancer Research Article Eleven patients suffering from intra-abdominal malignancy were treated with various doses of intraperitoneal mitomycin C adsorbed onto activated carbon particles. Seven of the patients underwent resection of their primary gastric tumour and all developed potentially life-threatening severe complications that proved to be fatal in four patients. The pattern of complications seen in these patients was unusual in patients undergoing gastrectomy and must be presumed to be secondary to the intraperitoneal mitomycin C. Intraperitoneal mitomycin C at a dose of 25 mg and 50 mg in the presence of an anastomosis or other suture line does not appear to be safe. Nature Publishing Group 1997 /pmc/articles/PMC2228208/ /pubmed/9413960 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Research Article
Ubhi, S. S.
McCulloch, P.
Veitch, P. S.
Preliminary results of the use of intraperitoneal carbon-adsorbed mitomycin C in intra-abdominal malignancy.
title Preliminary results of the use of intraperitoneal carbon-adsorbed mitomycin C in intra-abdominal malignancy.
title_full Preliminary results of the use of intraperitoneal carbon-adsorbed mitomycin C in intra-abdominal malignancy.
title_fullStr Preliminary results of the use of intraperitoneal carbon-adsorbed mitomycin C in intra-abdominal malignancy.
title_full_unstemmed Preliminary results of the use of intraperitoneal carbon-adsorbed mitomycin C in intra-abdominal malignancy.
title_short Preliminary results of the use of intraperitoneal carbon-adsorbed mitomycin C in intra-abdominal malignancy.
title_sort preliminary results of the use of intraperitoneal carbon-adsorbed mitomycin c in intra-abdominal malignancy.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2228208/
https://www.ncbi.nlm.nih.gov/pubmed/9413960
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AT veitchps preliminaryresultsoftheuseofintraperitonealcarbonadsorbedmitomycincinintraabdominalmalignancy

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