The influence of ifosfamide scheduling on acute nephrotoxicity in children.

Nephrotoxicity is a significant problem in children after treatment with ifosfamide. Acute changes in renal function were compared in 16 children receiving 9 g m(-2) of ifosfamide as a 72-h continuous infusion on one occasion and, on another course, divided into three 1-h infusions on consecutive da...

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Autores principales: English, M. W., Skinner, R., Pearson, A. D., Price, L., Wyllie, R., Craft, A. W.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1997
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2228242/
https://www.ncbi.nlm.nih.gov/pubmed/9155058
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author English, M. W.
Skinner, R.
Pearson, A. D.
Price, L.
Wyllie, R.
Craft, A. W.
author_facet English, M. W.
Skinner, R.
Pearson, A. D.
Price, L.
Wyllie, R.
Craft, A. W.
author_sort English, M. W.
collection PubMed
description Nephrotoxicity is a significant problem in children after treatment with ifosfamide. Acute changes in renal function were compared in 16 children receiving 9 g m(-2) of ifosfamide as a 72-h continuous infusion on one occasion and, on another course, divided into three 1-h infusions on consecutive days. Subclinical acute nephrotoxicity was demonstrated with both schedules, but there were no significant differences in severity.
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spelling pubmed-22282422009-09-10 The influence of ifosfamide scheduling on acute nephrotoxicity in children. English, M. W. Skinner, R. Pearson, A. D. Price, L. Wyllie, R. Craft, A. W. Br J Cancer Research Article Nephrotoxicity is a significant problem in children after treatment with ifosfamide. Acute changes in renal function were compared in 16 children receiving 9 g m(-2) of ifosfamide as a 72-h continuous infusion on one occasion and, on another course, divided into three 1-h infusions on consecutive days. Subclinical acute nephrotoxicity was demonstrated with both schedules, but there were no significant differences in severity. Nature Publishing Group 1997 /pmc/articles/PMC2228242/ /pubmed/9155058 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Research Article
English, M. W.
Skinner, R.
Pearson, A. D.
Price, L.
Wyllie, R.
Craft, A. W.
The influence of ifosfamide scheduling on acute nephrotoxicity in children.
title The influence of ifosfamide scheduling on acute nephrotoxicity in children.
title_full The influence of ifosfamide scheduling on acute nephrotoxicity in children.
title_fullStr The influence of ifosfamide scheduling on acute nephrotoxicity in children.
title_full_unstemmed The influence of ifosfamide scheduling on acute nephrotoxicity in children.
title_short The influence of ifosfamide scheduling on acute nephrotoxicity in children.
title_sort influence of ifosfamide scheduling on acute nephrotoxicity in children.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2228242/
https://www.ncbi.nlm.nih.gov/pubmed/9155058
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