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Gene expression profiling of leukemic cells and primary thymocytes predicts a signature for apoptotic sensitivity to glucocorticoids
BACKGROUND: Glucocorticoids (GC's) play an integral role in treatment strategies designed to combat various forms of hematological malignancies. GCs also are powerful inhibitors of the immune system, through regulation of appropriate cytokines and by causing apoptosis of immature thymocytes. By...
Autores principales: | Miller, Aaron L, Komak, Spogmai, Webb, M Scott, Leiter, Edward H, Thompson, E Brad |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2228275/ https://www.ncbi.nlm.nih.gov/pubmed/18045478 http://dx.doi.org/10.1186/1475-2867-7-18 |
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