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Receptor downregulation and desensitization enhance the information processing ability of signalling receptors
BACKGROUND: In addition to initiating signaling events, the activation of cell surface receptors also triggers regulatory processes that restrict the duration of signaling. Acute attenuation of signaling can be accomplished either via ligand-induced internalization of receptors (endocytic downregula...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2007
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2228318/ https://www.ncbi.nlm.nih.gov/pubmed/17996096 http://dx.doi.org/10.1186/1752-0509-1-48 |