Large and rapid changes in light scattering accompany secretion by nerve terminals in the mammalian neurohypophysis

Large changes in the opacity of the unstained mouse neurohypophysis follow membrane potential changes known to trigger the release of peptide hormones. These intrinsic optical signals, arising in neurosecretory terminals, reflect variations in light scattering and depend upon both the frequency of s...

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Detalles Bibliográficos
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1985
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2228802/
https://www.ncbi.nlm.nih.gov/pubmed/2997364
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collection PubMed
description Large changes in the opacity of the unstained mouse neurohypophysis follow membrane potential changes known to trigger the release of peptide hormones. These intrinsic optical signals, arising in neurosecretory terminals, reflect variations in light scattering and depend upon both the frequency of stimulation and [Ca2+]o. Their magnitude is decreased in the presence of Ca2+ antagonists and by the replacement of H2O in the medium by D2O. These observations suggest a correspondence between the intrinsic optical changes and secretory activity in these nerve terminals.
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spelling pubmed-22288022008-04-23 Large and rapid changes in light scattering accompany secretion by nerve terminals in the mammalian neurohypophysis J Gen Physiol Articles Large changes in the opacity of the unstained mouse neurohypophysis follow membrane potential changes known to trigger the release of peptide hormones. These intrinsic optical signals, arising in neurosecretory terminals, reflect variations in light scattering and depend upon both the frequency of stimulation and [Ca2+]o. Their magnitude is decreased in the presence of Ca2+ antagonists and by the replacement of H2O in the medium by D2O. These observations suggest a correspondence between the intrinsic optical changes and secretory activity in these nerve terminals. The Rockefeller University Press 1985-09-01 /pmc/articles/PMC2228802/ /pubmed/2997364 Text en This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Articles
Large and rapid changes in light scattering accompany secretion by nerve terminals in the mammalian neurohypophysis
title Large and rapid changes in light scattering accompany secretion by nerve terminals in the mammalian neurohypophysis
title_full Large and rapid changes in light scattering accompany secretion by nerve terminals in the mammalian neurohypophysis
title_fullStr Large and rapid changes in light scattering accompany secretion by nerve terminals in the mammalian neurohypophysis
title_full_unstemmed Large and rapid changes in light scattering accompany secretion by nerve terminals in the mammalian neurohypophysis
title_short Large and rapid changes in light scattering accompany secretion by nerve terminals in the mammalian neurohypophysis
title_sort large and rapid changes in light scattering accompany secretion by nerve terminals in the mammalian neurohypophysis
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2228802/
https://www.ncbi.nlm.nih.gov/pubmed/2997364

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