Cargando…
Maximal Ca2+-activated force and myofilament Ca2+ sensitivity in intact mammalian hearts. Differential effects of inorganic phosphate and hydrogen ions
Myofilament Ca2+ sensitivity and maximal Ca2+-activated force are fundamental properties of the contractile proteins in the heart. Although these properties can be evaluated directly in skinned preparations, they have remained elusive in intact tissue. A novel approach is described that allows maxim...
Formato: | Texto |
---|---|
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1987
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2228875/ https://www.ncbi.nlm.nih.gov/pubmed/3694173 |
Ejemplares similares
-
Ion Channel Impairment and Myofilament Ca(2+) Sensitization: Two Parallel Mechanisms Underlying Arrhythmogenesis in Hypertrophic Cardiomyopathy
por: Santini, Lorenzo, et al.
Publicado: (2021) -
Inorganic phosphate accelerates cardiac myofilament relaxation in response to lengthening
por: Wakefield, Jane I., et al.
Publicado: (2022) -
Why Is there a Limit to the Changes in Myofilament Ca(2+)-Sensitivity Associated with Myopathy Causing Mutations?
por: Marston, Steven B.
Publicado: (2016) -
Hypertrophic cardiomyopathy mutations increase myofilament Ca(2+) buffering, alter intracellular Ca(2+) handling, and stimulate Ca(2+)-dependent signaling
por: Robinson, Paul, et al.
Publicado: (2018) -
Cardiomyopathy mutation (F88L) in troponin T abolishes length dependency of myofilament Ca(2+) sensitivity
por: Reda, Sherif M., et al.
Publicado: (2018)