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N-ethylmaleimide uncouples muscarinic receptors from acetylcholine- sensitive potassium channels in bullfrog atrium
The effect of N-ethylmaleimide (NEM), a sulphydryl alkylating agent, on the acetylcholine-activated K+ current, IK(ACh), has been studied in single cells from bullfrog atrium using a tight-seal, whole-cell voltage clamp technique. Addition of NEM (5 x 10(-5) M) produced a time- dependent complete bl...
| Formato: | Texto |
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| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
1990
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2229007/ https://www.ncbi.nlm.nih.gov/pubmed/2175348 |