Cargando…
Evidence for a direct interaction between internal tetra-alkylammonium cations and the inactivation gate of cardiac sodium channels
The effects of internal tetrabutylammonium (TBA) and tetrapentylammonium (TPeA) were studied on human cardiac sodium channels (hH1) expressed in a mammalian tsA201 cell line. Outward currents were measured at positive voltages using a reversed Na gradient. TBA and TPeA cause a concentration-dependen...
Formato: | Texto |
---|---|
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1994
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2229220/ https://www.ncbi.nlm.nih.gov/pubmed/7807060 |
Ejemplares similares
-
Internal block of human heart sodium channels by symmetrical tetra- alkylammoniums
Publicado: (1994) -
Permeation of Large Tetra-Alkylammonium Cations through Mutant and Wild-Type Voltage-Gated Sodium Channels as Revealed by Relief of Block at High Voltage
por: Huang, Chien-Jung, et al.
Publicado: (2000) -
Ion association with tetra-n-alkylammonium cations stabilizes higher-oxidation-state neptunium dioxocations
por: Estes, Shanna L., et al.
Publicado: (2019) -
Interactions of monovalent cations with sodium channels in squid axon. I. Modification of physiological inactivation gating
Publicado: (1985) -
Interactions of monovalent cations with sodium channels in squid axon. II. Modification of pharmacological inactivation gating
Publicado: (1985)