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Adrenaline Stimulates Glucagon Secretion in Pancreatic A-Cells by Increasing the Ca(2+) Current and the Number of Granules Close to the L-Type Ca(2+) Channels
We have monitored electrical activity, voltage-gated Ca(2+) currents, and exocytosis in single rat glucagon-secreting pancreatic A-cells. The A-cells were electrically excitable and generated spontaneous Na(+)- and Ca(2+)-dependent action potentials. Under basal conditions, exocytosis was tightly li...
Autores principales: | Gromada, Jesper, Bokvist, Krister, Ding, Wei-Guang, Barg, Sebastian, Buschard, Karsten, Renström, Erik, Rorsman, Patrik |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1997
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2229364/ https://www.ncbi.nlm.nih.gov/pubmed/9276750 |
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