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Sodium Channel Inactivation Is Altered by Substitution of Voltage Sensor Positive Charges

The role of the voltage sensor positive charges in fast and slow inactivation of the rat brain IIA sodium channel was investigated by mutating the second and fourth conserved positive charges in the S4 segments of all four homologous domains. Both charge-neutralizing mutations (by glutamine substitu...

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Detalles Bibliográficos
Autores principales:	Kontis, Kris J., Goldin, Alan L.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 1997
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2229380/ https://www.ncbi.nlm.nih.gov/pubmed/9379172

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