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Cyclic Nucleotide–Gated Channels: Pore Topology Studied through the Accessibility of Reporter Cysteines
In voltage- and cyclic nucleotide–gated ion channels, the amino-acid loop that connects the S5 and S6 transmembrane domains, is a major component of the channel pore. It determines ion selectivity and participates in gating. In the α subunit of cyclic nucleotide–gated channels from bovine rod, the p...
Autores principales: | Becchetti, Andrea, Gamel, Katia, Torre, Vincent |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1999
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2229457/ https://www.ncbi.nlm.nih.gov/pubmed/10469728 |
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