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μ-Conotoxin Giiia Interactions with the Voltage-Gated Na(+) Channel Predict a Clockwise Arrangement of the Domains

Voltage-gated Na(+) channels underlie the electrical activity of most excitable cells, and these channels are the targets of many antiarrhythmic, anticonvulsant, and local anesthetic drugs. The channel pore is formed by a single polypeptide chain, containing four different, but homologous domains th...

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Detalles Bibliográficos
Autores principales:	Dudley, Samuel C., Chang, Nancy, Hall, Jon, Lipkind, Gregory, Fozzard, Harry A., French, Robert J.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2000
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2229485/ https://www.ncbi.nlm.nih.gov/pubmed/11055996

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