Severed Molecules Functionally Define the Boundaries of the Cystic Fibrosis Transmembrane Conductance Regulator's Nh(2)-Terminal Nucleotide Binding Domain

The cystic fibrosis transmembrane conductance regulator is a Cl(−) channel that belongs to the family of ATP-binding cassette proteins. The CFTR polypeptide comprises two transmembrane domains, two nucleotide binding domains (NBD1 and NBD2), and a regulatory (R) domain. Gating of the channel is cont...

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Detalles Bibliográficos
Autores principales: Chan, Kim W., Csanády, László, Seto-Young, Donna, Nairn, Angus C., Gadsby, David C.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2000
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2229491/
https://www.ncbi.nlm.nih.gov/pubmed/10919864

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